Epping Private Hospital and Medical Centre caters to surgical and medical specialties and is anchored by a 24-bed, four-theatre hospital and day surgery that is occupied by Northern Health, who now take up 49 per cent of the building.

Other major tenants and health faculties include Genesis (oncology), I-Med (radiology), Melbourne Pathology, and Family Doctors (general practice) and a number of specialist and consulting suites.